Andreas, Neubauer, Prof. Dr. (C3)

Original articles:

Görg C, Wollenberg B, Beyer J, Stolte MS, Neubauer A
High-resolution ultrasonography in gastrointestinal graft-versus-host disease.
Ann Hematol 84: 33-39, 2005.

Illmer T, Thiede, C., Fredersdorf, A., Stadler, S., Neubauer, A., Ehninger, G., Schaich, M.
Activation of the RAS pathway is predictive for a chemosensitive phenotype of acute myelogenous leukemia blasts.
Clin Cancer Res, 11: 3217-24, 2005

Seifart U, Jensen K, Ukena J, Mueller C, Schröder M, Fuhr HG, Keppler U, Neubauer A, Staab HJ, Wolf M.
Randomized phase II study comparing topotecan cisplatinum administration for 5 days versus 3 days in the treatment of extensive stage small cell lung cancer (SCLC).
Lung cancer 2005; 48: 415-422.

Stelljes M, Bornhäuser M, Kröger M, Beyer J, Sauerland MC, Heinecke A, Berning B, Scheffold C, Silling G, Büchner T, Neubauer A, Fauser AA, Ehninger G, Berdel W, Kienast J.
Conditioning with 8 Gy total body irradiation and fludarabine for allogeneic hematopoietic stem cell transplantation in acute myeloid leukemia.
Blood 106: 3314-21, 2005.

Burchert A., Wang Y, Cai D, Bubnoff Nv, Paschka P, Müller-Brüsselbach S, Ottmann OG, Duyster J, Hochhaus A, Neubauer A.
Compensatory PI3-Kinase/Akt/mTor activation regulates Imatinib resistance development.
Leukemia, 19: 1774-82, 2005.

Rinn J, Schwella N, Wollmer E, Jaques G, Heinzel-Gutenbrunner M, Strassmann G, Gross MW, Movassaghi K, Neubauer A, Ritter M.
Local irradiation prior to stem cell harvest has no influence on CD34+ yield: a quantitative analysis.
Ann Hematol 85:38-44, 2006.

Lenz, G.,Dreyling, M., Hoster, E., Wormann, B., Duhrsen, U., Metzner, B., Eimermacher, H., Neubauer, A., Wandt, H., Steinhauer, H., Martin, S., Heidemann, E., Aldaoud, A., Parwaresch, R., Hasford, J., Unterhalt, M., Hiddemann, W.
Immunochemotherapy With Rituximab and Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone Significantly Improves Response and Time to Treatment Failure, But Not Long-Term Outcome in Patients With Previously Untreated Mantle Cell Lymphoma: Results of a Prospective Randomized Trial of the German Low Grade Lymphoma Study Group (GLSG).
J. Clin. Oncol. 23 (9): 1984-1992, 2005.

Wündisch T, Thiede C, Morgner A, Dempfle A, Günther A, Liu H, Ye H, Du M, Kim TD, Bayerdörffer E, Stolte M, Neubauer A.
Long-term follow-up of 120 patients with gastric MALT lymphoma after Helicobacter pylori eradication.
J Clin Oncol 23: 8018-24, 2005

Dickhut A, Schwerdtfeger R, Kuklick L, Ritter M, Thiede C, Neubauer A, Brendel C.
Mesenchymal stem cells obtained after bone marrow transplantation or peripheral blood stem cell transplantation originate from host tissue.
Ann Hematol 84: 722-727, 2005.

Cai D, Wang Y, Ottmann OG, Barth PJ, Neubauer A, Burchert A.
FLT3-ITD-, but not BCR/ABL-transformed cells require concurrent Akt/mTor blockage to undergo apoptosis after histone deacetylase inhibitor treatment.
Blood 107 2094-2097, 2006.

Ortmann C, Burchert A, Hölzle K, Nitsche A, Wittig B, Neubauer A, Schmidt M.
Down-regulation of interferon regulatory factor 4 gene expression in leukemic cells due to hypermethylation of CpG motifs in the promoter region.
Nucl Acids Res, 33: 6895-6905, 2005

Bug G, Ritter M, Wassmann B, Schoch C, Heinzel T, Schwarz K, Romanski A, Kramer OH, Kampfmann M, Hoelzer D, Neubauer A, Ruthardt M, Ottmann OG.
Clinical trial of valproic acid and all-trans retinoic acid in patients with poor-risk acute myeloid leukemia.
Cancer 104: 2717-2725, 2005.

Ritter M, Kattmann D, Teichler S, Hartmann O, Samuelsson MKR, Burchert A, Bach JP, Kim TD, Berwanger B, Thiede C, Jäger R, Ehninger G, Schäfer H, Ueki N, Hayman MJ, Eilers M, Neubauer A.
Inhibition of retinoic acid signaling by Ski in acute myeloid leukemia.
Leukemia 20: 437-443, 2006.

Brendel C, Kuklick L., Hartmann O., Kim TD, Boudriot U, Schwell D, Neubauer, A.
Distinct gene expression profile of human mesenchymal stem cells in comparison to skin fibroblasts employing cDNA microarray analysis of 9600 genes.
Gene Expression 12: 245-57, 2005.

Ye H, Gong L, Liu H, Ruskone-Fourmestraux A, de Jong D, Pileri S, Thiede C, Lavergne A, Boot H, Caletti G, Wundisch T, Molina T, Taal BG, Elena S, Neubauer A, Maclennan KA, Siebert R, Remstein ED, Dogan A, Du MQ.: Strong BCL10 nuclear expression identiN Kröger, M Frick, O Gluz, S Mohrmann, B Metzner, Ch Jackisch, Y. Ko, H Eimermacher, CR Meier, H P Lohrmann, U Ruffert, M Hänel, H Bodenstein, A Neubauer, G Ehninger, HJ Schmoll, K Kolbe, A Hinke, K Mählmann, A R. Zander, U. Nitz
Randomized trial of single versus tandem high-dose chemotherapy (STAMP V) followed by autologous stem cell transplantation in patients with chemosensitive metastatic breast cancer.
J Clin Oncol 2006, 24:3919-26

Sohlbach K, Heinze S, Shiratori K, Sure U, Pagenstecher A, Neubauer A.
Encephalopathy In A Patient After Long-Term Treatment With Thalidomide (Case report).
J Clin Oncol, 24: 4942-44, 2006

Mandic R, Rodgarkia-Dara CJ, Zhu L, Folz BJ, Bette M, Weihe E, Neubauer A, Werner JA.
Treatment of HNSCC cell lines with the EGFR-specific inhibitor cetuximab (Erbitux®) results in paradox phosphorylation of tyrosine 1173 in the receptor.
FEBS Lett. 2006, 580: 4793-4800.

Dunne J, Cullmann C, Ritter M, Soria NM, Drescher B, Debernardi S, Skoulakis S, Hartmann O, Krause M, Krauter J, Neubauer A, Young BD, Heidenreich O.
siRNA-mediated AML1/MTG8 depletion affects differentiation and proliferation-associated gene expression in t(8;21)-positive cell lines and primary AML blasts.
Oncogene. 2006; 25: 6067-78

Wilhelm C, Neubauer A, Brendel C.
Discordant results of flow cytometric ZAP-70 expression status in B-CLL samples if different gating strategies are applied.
Cytometry B, Clin Cytometry 70B(4):242-250, 2006.

Bach JP, Kiessling AM, Kleinhans A, Faoro C, Gorg C, Riera-Knorrenschild J, Schwella N, Wagner HJ, Neubauer A.
Pulmonary fibrosis in a patient treated with erlotinib (Case report).
Onkologie 29(7):342-3, 2006.

Wündisch T, Mösch C, Neubauer A, Stolte M.
Helicobacter pylori eradication in gastric mucosa associated lymphoid tissue lymphoma: Results of a 196-case series.
Leuk Lymphoma 47: 2110-14, 2006

Mey, U.J.M., Orlopp, K.S., Flieger, D., Strehl, J.W., Ho, A.D., Hensel, M., Bopp, C., Gorschlüter, M., Wilhelm, M., Birkmann, J., Kaiser, U., Neubauer, A., Florschütz, A., Rabe, Chr., Hahn, C., Glasmacher, A. und Schmidt-Wolf I.G.H.
Dexamethasone, High-Dose Cytarabine, and Cisplatin in Combination with Rituximab as Salvage Treatment for Patients with Relapsed or Refractory Aggressive Non-Hodgkin`s Lymphoma.
Cancer Investigation, 24: 593-600, 2006.

Wang Y, Cai D, Brendel C, Barett C, Erben P, Manley PW, Hochhaus A, Neubauer A, and Burchert A.
Adaptive secretion of the Granulocyte Macrophage Colony Stimulating Factor (GM-CSF) mediates Imatinib- and Nilotinib-resistance in BCR/ABL-positive progenitors via JAK-2/STAT-5 pathway activation.
Blood, 2007; 109:2147-55.

Brendel C, Scharenberg C, Gessner M, Robey R, Burchert A, Hoffmann J, Boudriot U, Jaques G, Neubauer A.
Imatinib mesylate and nilotinib (AMN107) exhibit high-affinity interaction with ABCG2 on primitive hematopoietic stem cells.
Leukemia, 21: 1267-75, 2007.

Dror N, Rave-Harel N, Burchert A, Azriel A, Tamura T, Tailor P, Neubauer A, Ozato K, Levi BZ.
Interferon Regulatory Factor-8 Is Indispensable for the Expression of Promyelocytic Leukemia and the Formation of Nuclear Bodies in Myeloid Cells.
J Biol Chem 2007; 282: 5633–5640.

Kreutzer M, Fauti T, Kaddatz K, Seifart C, Neubauer A, Schweer H, Kömhoff M, Müller-Brüsselbach S, Müller R.
Specific components of prostanoid-signaling pathways are present in non-small cell lung cancer cells.
Oncology Rep, 18: 497-501, 2007

Mack E, Neubauer A, Brendel C.
Comparison of RNA yield from small cell populations sorted by flow cytometry applying different isolation procedures.
Cytometry A, 71A, 404-409, 2007.

Herold, M., Haas, A., Srock, S., Neser, S., Al-Ali, K. H., Neubauer, A., Dolken, G., Naumann, R., Knauf, W., Freund, M., Rohrberg, R., Hoffken, K., Franke, A., Ittel, T., Kettner, E., Haak, U., Mey, U., Klinkenstein, C., Assmann, M., von Grunhagen, U.
Rituximab added to first-line mitoxantrone, chlorambucil, and prednisolone chemotherapy followed by interferon maintenance prolongs survival in patients with advanced follicular lymphoma: an East German Study Group Hematology and Oncology Study.
J Clin Oncol 25: 1986-92, 2007.

Srock, S., Schriever, F., Neubauer, A., Herold, M., Huhn, D.
Long-term treatment with rituximab is feasible in selected patients with B-CLL: Response-adjusted low-dose maintenance treatment with rituximab in patients with relapsed B-CLL, who achieved a partial or minimal response to prior rituximab therapy.
Leukemia and Lymphoma 48: 905-911, 2007.

Fischbach W, Goebeler ME, Ruskone- Fourmestraux A, Wündisch T, Neubauer A, Savio A, Raderer M.
Most patients with minimal histological residuals of gastric MALT lymphoma after successful eradication of Helicobacter pylori can be safely managed by a watch-and-wait strategy. Experience from a large international series.
Gut, 56: 1685-87, 2007.

Hagenah GC, Wündisch T, Eckstein E, Zimmermann S, Holst F, Grimm W, Neubauer A, Lohoff M.
Sepsis-like disease in an immunocompromised patient with travel history to Mallorca (Case report).
Internist 48:727-730, 2007.

Mikesch J., Burchert A., Kress O., Ritter M., Görg C., Neubauer A.
Diffuse pneumatosis due to central venous catherization in a patient with acute graft versus host disease.
Ann Hematol 86: 767-69, 2007 (Letter).

Neubauer A, Maharry K, Mrózek K, Thiede C, Marcucci G, Paschka P, Mayer RJ, Larson RA, Liu ET, and Bloomfield CD.
Patients with acute myeloid leukemia and RAS mutations benefit most from postremission treatment with high-dose cytarabine: a Cancer and Leukemia Group B study.
J Clin Oncol, in press 2008.

Schulz S, Häussler U, Mandic R, Heverhagen JT, Neubauer A, Dünne AA, Werner JA, Weihe E, and Bette M.
Treatment with ozone/oxygen-pneumoperitoneum results in complete remission of rabbit squamous cell carcinomas.
Int J Cancer 122: 2360-67, 2008.

Huynh M, Wacker HH, Wündisch T, Sohlbach K, Kim TD, Krause M, Stabla K, Roth P, Fischbach W, Stolte M, Neubauer A.
Expression profiling reveals specific gene expression signatures in gastric MALT lymphomas.
Leuk Lymphoma, in press 2008.

Teichler S, Schlenk RF, Strauch K, Hagner N, Ritter M, Neubauer A.
Expression of the nuclear oncogene Ski in patients with acute myeloid leukemia treated with all-trans retinoic acid.
Haematologica, in press 2008.

Knoll S, Zimmer S, Hinney A, Scherag A, Neubauer A, Hebebrand J.
Val103Ile polymorphism of the melanocortin-4 receptor gene (MC4R) in cancer cachexia.
BMC Cancer, in press 2008.